LINC01455

Across TCGA pan-cancer cohorts, LINC01455 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC01455 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher LINC01455 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01455 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

ESCA, LGG, and OV are the cancer types where LINC01455 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	IV	0.095	0.512	.008	54	view →
LGG	DFS	Tertile	All	0.386	0.747	<.001	42	view →
OV	OS	Tertile	IV	0.123	0.771	.001	36	view →
LUAD	DFS	Tertile	II,III,IV	0.884	0.665	.014	33	view →
THCA	DFS	Tertile	All	0.166	0.826	<.001	33	view →
KIRC	DFS	Tertile	All	0.570	0.802	.023	24	view →
LIHC	OS	Tertile	All	0.164	0.704	.025	18	view →
BRCA	DFS	Tertile	III,IV	0.582	0.801	.022	12	view →
PRAD	OS	Tertile	All	0.265	0.884	<.001	12	view →
LUSC	OS	Tertile	II,III,IV	0.249	0.615	.048	9	view →
MESO	OS	Tertile	II,III,IV	0.180	0.560	.046	9	view →
HNSC	OS	Tertile	All	0.786	0.346	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

LINC01455–ESCA (OS)

Open the ESCA breakdown →