LINC01397

Across TCGA pan-cancer cohorts, LINC01397 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01397’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01397 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01397 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

LUAD, KIRC, and CHOL are the cancer types where LINC01397 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01397 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.248	<.001	8	view →
KIRC	All	All	+0.081	<.001	7	view →
CHOL	All	II,III,IV	+0.455	<.001	4	view →
BRCA	Female	All	−0.306	<.001	4	view →
LUSC	All	All	+0.197	<.001	4	view →
BRCA	All	IV	+0.815	.046	2	view →
BLCA	Male	All	+0.356	.046	2	view →
LIHC	Male	All	+0.157	.006	2	view →
COAD	All	II,III,IV	+0.079	.016	2	view →
HNSC	Female	III,IV	+0.180	.032	1	view →
STAD	Male	II,III,IV	+0.162	.005	1	view →
KIRP	All	III,IV	+0.144	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01397–LUAD

Open the LUAD breakdown →