long intergenic non-protein coding RNA 1358Genealiases: []
Q-omics provides the consensus-scored LINC01358 profile across patient tissues and cancer cell-line models. LINC01358 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, LINC01358 is differentially expressed in 11, with the highest sampling consensus in KIRC. Additionally, LINC01358 RNA expression shows 14,823 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight SKCM, KIRC, and LSCC as cancer lineages where LINC01358 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01358 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01358 survival associations across molecular data types. LINC01358 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01358 RNA expression–survival associations across cancer types. High LINC01358 expression shows unfavorable associations in KIRP, LGG and UVM, but favorable associations in SKCM, KIRC and STAD. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for LINC01358 RNA expression.
This table summarizes LINC01358 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01358. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01358 shows lower tumor expression in UCEC, BRCA, KICH and THCA and higher tumor expression in KIRC and LIHC. The KIRC box plot shows higher LINC01358 RNA expression in tumor versus normal tissue (log2 FC = +2.163, t-test p < 0.001).
This table shows molecular features associated with LINC01358 in patient tissues and cancer cell lines. In patient samples, LINC01358 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
