Across TCGA pan-cancer cohorts, LINC01304 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01304’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01304 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01304 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.
THCA and BRCA are the cancer types where LINC01304 tumor–normal differential expression is most reproducible.