LINC01259

Across TCGA pan-cancer cohorts, LINC01259 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC01259 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LINC01259 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01259 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

UCEC, ESCA, and COAD are the cancer types where LINC01259 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.250	0.615	<.001	96	view →
ESCA	OS	Median	III,IV	0.591	0.297	.001	42	view →
COAD	OS	Tertile	IV	0.172	0.688	<.001	36	view →
LUAD	OS	Median	All	0.773	0.639	<.001	35	view →
SKCM	OS	Tertile	All	0.954	0.834	.007	32	view →
PAAD	OS	Quartile	II,III,IV	0.860	0.546	.004	31	view →
UVM	OS	Tertile	II,III,IV	0.104	0.829	<.001	27	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	27	view →
DLBC	DFS	Quartile	All	0.291	0.896	.003	26	view →
KIRP	DFS	Tertile	III,IV	0.040	0.691	<.001	18	view →
LGG	DFS	Tertile	All	0.210	0.485	.005	18	view →
OV	OS	Tertile	II,III,IV	0.418	0.304	.039	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC01259–UCEC (DFS)

Open the UCEC breakdown →