long intergenic non-protein coding RNA 1254Genealiases: []
Q-omics provides the consensus-scored LINC01254 profile across patient tissues and cancer cell-line models. LINC01254 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, LINC01254 is differentially expressed in 5, with the highest sampling consensus in HNSC. Additionally, LINC01254 RNA expression shows 6,136 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, HNSC, and THYM as cancer lineages where LINC01254 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01254 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01254 survival associations across molecular data types. LINC01254 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01254 RNA expression–survival associations across cancer types. High LINC01254 expression shows unfavorable associations in KICH, LIHC, KIRC, THCA, READ and UVM. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for LINC01254 RNA expression.
This table summarizes LINC01254 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01254. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01254 shows lower tumor expression in KIRC and BRCA and higher tumor expression in HNSC, LUSC and BLCA. The HNSC box plot shows higher LINC01254 RNA expression in tumor versus normal tissue (log2 FC = +0.276, t-test p = .001).
This table shows molecular features associated with LINC01254 in patient tissues and cancer cell lines. In patient samples, LINC01254 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
