LINC01251

Across TCGA patient cohorts, LINC01251 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01251-associated GO terms across cancer lineages are Regulation of DNA repair, Nucleolar large rRNA transcription by RNA polymerase I, and Regulation of DNA-directed DNA polymerase activity. Each is linked with LINC01251 in more than 16 cancer types. Because this analysis shows association rather than direction, both LINC01251-to-partner and partner-to-LINC01251 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by LINC01251-low versus LINC01251-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01251→partner) and Y-score (partner→LINC01251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.053	+0.438	<.001	<.001	3	17
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.050	+0.362	<.001	<.001	3	17
THYM	Regulation of DNA-directed DNA polymerase activity →	+0.071	+0.574	<.001	<.001	3	16
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.051	+0.476	<.001	<.001	3	16
STAD	DNA replication →	+0.061	+0.424	<.001	<.001	3	16
ESCA	rRNA transcription →	+0.062	+0.465	.003	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

Regulation of DNA repair by LINC01251 expression — STAD

Explore this box plot interactively →