LINC01251

Across TCGA pan-cancer cohorts, LINC01251 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01251’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01251 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01251 is over-expressed in tumor, although a few such as READ and COAD show the opposite, repressed pattern.

LIHC, READ, and COAD are the cancer types where LINC01251 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01251 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.178	.009	5	view →
READ	All	All	−0.647	.004	3	view →
COAD	All	III,IV	−0.450	.003	3	view →
LUSC	All	All	+0.195	<.001	3	view →
UCEC	All	All	+0.387	.013	2	view →
KICH	All	All	−0.109	.016	2	view →
BLCA	Male	III,IV	+0.355	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC01251–LIHC

Open the LIHC breakdown →