LINC01227

Across TCGA patient cohorts, LINC01227 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,646 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01227-associated GO terms across cancer lineages are Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, Regulation of DNA binding, and Positive regulation of DNA biosynthetic process. Each is linked with LINC01227 in more than 14 cancer types. Because this analysis shows association rather than direction, both LINC01227-to-partner and partner-to-LINC01227 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum grouped by LINC01227-low versus LINC01227-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01227→partner) and Y-score (partner→LINC01227) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.071	+0.097	<.001	<.001	3	15
STAD	Regulation of DNA binding →	+0.060	+0.104	<.001	<.001	3	14
STAD	Positive regulation of DNA biosynthetic process →	+0.077	+0.104	<.001	<.001	3	14
STAD	Protein stabilization →	+0.071	+0.095	<.001	<.001	3	14
STAD	Positive regulation of DNA metabolic process →	+0.072	+0.114	<.001	<.001	3	14
ESCA	Protein folding →	+0.071	+0.070	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,646 associations by consensus.

Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum by LINC01227 expression — STAD

Explore this box plot interactively →