LINC01227

Across TCGA pan-cancer cohorts, LINC01227 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01227’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01227 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01227 is over-expressed in tumor.

BRCA, LUAD, and HNSC are the cancer types where LINC01227 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01227 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.035	.002	4	view →
LUAD	Male	All	+0.032	.002	4	view →
HNSC	Male	IV	+0.017	.037	3	view →
KIRC	All	All	+0.008	.013	3	view →
PRAD	All	All	+0.052	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01227–BRCA

Open the BRCA breakdown →