long intergenic non-protein coding RNA 1140Genealiases: []
Q-omics provides the consensus-scored LINC01140 profile across patient tissues and cancer cell-line models. LINC01140 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, LINC01140 is differentially expressed in 13, with the highest sampling consensus in THCA. Additionally, LINC01140 RNA expression shows 17,175 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight UCS, THCA, and DLBC as cancer lineages where LINC01140 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01140 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01140 survival associations across molecular data types. LINC01140 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01140 RNA expression–survival associations across cancer types. High LINC01140 expression shows unfavorable associations in UVM, LIHC, UCEC, KIRP and BLCA, but favorable associations in UCS. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for LINC01140 RNA expression.
This table summarizes LINC01140 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01140. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01140 shows lower tumor expression in THCA, COAD, LUAD, BRCA, UCEC and HNSC. The THCA box plot shows higher LINC01140 RNA expression in normal versus tumor tissue (log2 FC = −0.624, t-test p < 0.001).
This table shows molecular features associated with LINC01140 in patient tissues and cancer cell lines. In patient samples, LINC01140 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC01140 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Lymphoma and NCI60_ALL.
