LINC01116

Across TCGA patient cohorts, LINC01116 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01116-associated genes across cancer lineages are DEFA7P, RNU6-206P, and RNU6-73P. Each is linked with LINC01116 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01116-to-partner and partner-to-LINC01116 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA7P grouped by LINC01116-low versus LINC01116-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01116→partner) and Y-score (partner→LINC01116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DEFA7P →	+0.292	+4.453	<.001	.006	3	1
UCEC	RNU6-206P →	+0.372	+5.245	<.001	.002	3	1
UCEC	RNU6-73P →	+0.504	+4.226	<.001	.008	3	1
UCEC	CALM1P1 →	+0.492	+3.680	<.001	.007	3	1
UCEC	TOMM22P5 →	+0.304	+3.576	.006	.009	3	1
UCEC	SAR1AP1 →	+0.341	+3.798	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

DEFA7P by LINC01116 expression — UCEC

Explore this box plot interactively →