LINC01098

Across TCGA patient cohorts, LINC01098 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01098-associated genes across cancer lineages are EGFR_pY1068, Shc_pY317, and Heregulin. Each is linked with LINC01098 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01098-to-partner and partner-to-LINC01098 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by LINC01098-low versus LINC01098-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01098→partner) and Y-score (partner→LINC01098) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.339	-3.321	.009	.010	3	1
UCEC	Shc_pY317 →	-0.251	-3.169	.001	.019	3	1
UCEC	Heregulin →	-0.135	-3.000	.036	.036	2	1
UCEC	p70-S6K_pT389 →	-0.237	-2.990	.017	.036	2	1
UCEC	Di-Ras3 →	-0.188	-3.000	.015	.036	2	1
UCEC	JNK2 →	+0.275	+3.321	.008	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

EGFR_pY1068 by LINC01098 expression — UCEC

Explore this box plot interactively →