LINC01010

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01010 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01010-associated genes across cancer lineages are MIR521-2, RPSAP64, and LINC02022. Each is linked with LINC01010 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01010-to-partner and partner-to-LINC01010 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR521-2 grouped by LINC01010-low versus LINC01010-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01010→partner) and Y-score (partner→LINC01010) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR521-2 →+0.481+4.484<.001.00931
UCECRPSAP64 →+0.395+4.499<.001.00531
UCECLINC02022 →+0.690+4.279<.001.00831
UCECUBE2V1P4 →+0.240+4.484.004.00931
UCECFAM138E →+0.080+4.771<.001.00631
UCECRNU6-1213P →+0.528+5.877<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MIR521-2 by LINC01010 expression — UCEC

Box plot of MIR521-2 in LINC01010-low vs LINC01010-high samples in UCEC.

Explore this box plot interactively →

Exploration