LINC00997

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00997 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LINC00997 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC00997 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00997 expression acts as an unfavorable survival marker.

LUAD and SKCM are the cancer types where LINC00997 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.2450.835<.00115view →
SKCMDFSMedianAll0.0090.738<.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

LINC00997–LUAD (OS)

Kaplan–Meier survival curve for LINC00997 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration