LINC00997

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00997 mutation is significantly associated with the RNA expression of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00997-associated genes across cancer lineages are CKS1BP6, MAP3K9, and COX6CP3. Each is linked with LINC00997 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00997-to-partner and partner-to-LINC00997 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CKS1BP6 grouped by LINC00997-low versus LINC00997-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00997→partner) and Y-score (partner→LINC00997) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCKS1BP6 →+0.560+3.089<.001.00331
UCECMAP3K9 →+0.635+3.226.004.00931
UCECCOX6CP3 →+0.204+3.092.004.00331
UCECMIR98 →+0.462+3.216<.001.00231
UCECMIR6124 →+0.418+2.766.003.00731
UCECSTMN1P1 →+0.538+3.330.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

CKS1BP6 by LINC00997 expression — UCEC

Box plot of CKS1BP6 in LINC00997-low vs LINC00997-high samples in UCEC.

Explore this box plot interactively →

Exploration