LINC00973

Across TCGA pan-cancer cohorts, LINC00973 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated LINC00973 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00973 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00973 expression acts as an unfavorable survival marker, although some lineages such as CHOL and DLBC show a favorable association.

KIRC, KIRP, and ACC are the cancer types where LINC00973 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.502	0.706	<.001	144	view →
KIRP	OS	Median	II,III,IV	0.349	0.791	<.001	102	view →
ACC	OS	Tertile	All	0.366	0.728	<.001	86	view →
STAD	OS	Median	IV	0.176	0.511	.005	82	view →
BRCA	DFS	Median	III,IV	0.816	0.915	.001	76	view →
LUSC	OS	Quartile	All	0.724	0.829	.005	54	view →
COAD	DFS	Quartile	All	0.596	0.725	.005	33	view →
READ	OS	Quartile	IV	0.548	0.951	.007	30	view →
HNSC	OS	Tertile	All	0.711	0.800	.013	25	view →
CHOL	DFS	Quartile	II,III,IV	1.000	0.146	.011	21	view →
MESO	OS	Quartile	All	0.217	0.423	.001	20	view →
PAAD	OS	Median	All	0.300	0.456	.009	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

LINC00973–KIRC (DFS)

Open the KIRC breakdown →