LINC00945

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00945 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,715 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LINC00945-associated proteins across cancer lineages are PDK1, PDZD11, and AMPD3_S85. Each is linked with LINC00945 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINC00945-to-partner and partner-to-LINC00945 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC00945 versus PDK1 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00945→partner) and Y-score (partner→LINC00945) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPDK1 →-0.441-0.757<.001.00133
GBMPDZD11 →-0.416-0.713<.001.00133
COADAMPD3_S85 →+0.323+0.033.006.00632
GBMZFP64 →+0.437+1.040.002<.00132
UCECARFGEF2_T244 →+0.721+0.309.001.00932
LUADOCRL →+0.182+0.418<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,715 associations by consensus.

LINC00945 vs PDK1 — GBM

Per-sample scatter of LINC00945 vs PDK1 in GBM (Pearson r = -0.37).

Explore this scatter interactively →

Exploration