LINC00945

Across TCGA pan-cancer cohorts, LINC00945 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LINC00945 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00945 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00945 expression acts as an unfavorable survival marker, although some lineages such as LAML and OV show a favorable association.

UVM, KIRC, and HNSC are the cancer types where LINC00945 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.271	0.652	<.001	144	view →
KIRC	DFS	Tertile	All	0.475	0.710	.001	66	view →
HNSC	DFS	Tertile	All	0.570	0.708	.007	51	view →
CESC	DFS	Tertile	II,III,IV	0.433	0.726	.007	48	view →
BLCA	DFS	Tertile	IV	0.171	0.390	.015	36	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	36	view →
DLBC	DFS	Quartile	IV	0.146	0.731	<.001	35	view →
READ	DFS	Tertile	III,IV	0.082	0.749	<.001	27	view →
PAAD	DFS	Tertile	All	0.274	0.529	.013	18	view →
LIHC	OS	Tertile	All	0.584	0.794	.017	18	view →
LAML	DFS	Tertile	All	0.529	0.278	.004	16	view →
OV	DFS	Tertile	III,IV	0.205	0.144	.033	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LINC00945–UVM (OS)

Open the UVM breakdown →