Across TCGA pan-cancer cohorts, LINC00934 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC00934’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LINC00934 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00934 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.
BLCA, THCA, and KIRP are the cancer types where LINC00934 tumor–normal differential expression is most reproducible.