LINC00886

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00886 mutation is significantly associated with the RNA expression of many other genes, with 1,112 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00886-associated genes across cancer lineages are MIR938, RNY4P16, and MIR620. Each is linked with LINC00886 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINC00886-to-partner and partner-to-LINC00886 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR938 grouped by LINC00886-low versus LINC00886-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00886→partner) and Y-score (partner→LINC00886) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR938 →+0.326+2.302.008.00333
LUSCRNY4P16 →+0.243+4.733<.001.00432
LUSCMIR620 →+0.271+4.906<.001.00332
UCECRNA5SP140 →+1.198+2.937<.001.00232
BRCASDR42E1P1 →+0.053+8.057<.001.00531
SKCMMIR4487 →+0.493+7.816<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,112 associations by consensus.

MIR938 by LINC00886 expression — UCEC

Box plot of MIR938 in LINC00886-low vs LINC00886-high samples in UCEC.

Explore this box plot interactively →

Exploration