LINC00886

Across TCGA pan-cancer cohorts, LINC00886 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LINC00886 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00886 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00886 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, KIRP, and MESO are the cancer types where LINC00886 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.724	0.541	<.001	75	view →
KIRP	OS	Quartile	All	0.976	0.829	<.001	59	view →
MESO	OS	Median	All	0.642	0.441	.001	53	view →
LGG	DFS	Median	All	0.644	0.825	<.001	51	view →
BLCA	DFS	Quartile	II,III,IV	0.680	0.527	.010	36	view →
ACC	OS	Median	II,III,IV	0.956	0.757	.016	35	view →
GBM	DFS	Median	All	0.192	0.312	.003	26	view →
SARC	DFS	Median	All	0.720	0.457	<.001	25	view →
BRCA	OS	Tertile	IV	0.652	0.168	.008	21	view →
UVM	DFS	Median	All	0.773	0.366	.003	18	view →
CESC	DFS	Tertile	IV	0.693	0.251	.013	18	view →
PAAD	OS	Median	II,III,IV	0.515	0.285	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LINC00886–KIRC (DFS)

Open the KIRC breakdown →