LINC00886

Across TCGA patient cohorts, LINC00886 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00886-associated genes across cancer lineages are EGFR_pY1068, ACC1, and INPP4B. Each is linked with LINC00886 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00886-to-partner and partner-to-LINC00886 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by LINC00886-low versus LINC00886-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00886→partner) and Y-score (partner→LINC00886) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.268	-2.584	.021	.011	3	1
UCEC	ACC1 →	+0.346	+2.584	.041	.011	3	1
UCEC	INPP4B →	-0.312	-2.571	.038	.011	3	1
UCEC	Ku80 →	+0.267	+3.009	.015	.019	3	1
UCEC	Notch1 →	+0.186	+2.331	.004	.019	3	1
UCEC	PDCD4 →	-0.614	-2.312	.005	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

EGFR_pY1068 by LINC00886 expression — UCEC

Explore this box plot interactively →