LINC00869

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00869 mutation is significantly associated with the RNA expression of many other genes, with 4,410 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00869-associated genes across cancer lineages are RPS15AP3, OR7A8P, and SELENOTP2. Each is linked with LINC00869 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINC00869-to-partner and partner-to-LINC00869 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS15AP3 grouped by LINC00869-low versus LINC00869-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00869→partner) and Y-score (partner→LINC00869) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRPS15AP3 →+0.223+5.273<.001.00634
CESCOR7A8P →+0.093+3.590<.001.00232
CESCSELENOTP2 →+0.087+3.269<.001.00932
SKCMPRPF18 →+0.661+3.208.001.00932
UCECRRM1 →+1.028+2.807<.001<.00132
UCECFEN1 →+0.749+2.839<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,410 associations by consensus.

RPS15AP3 by LINC00869 expression — LUSC

Box plot of RPS15AP3 in LINC00869-low vs LINC00869-high samples in LUSC.

Explore this box plot interactively →

Exploration