LINC00869

Across TCGA pan-cancer cohorts, LINC00869 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00869’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00869 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00869 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KIRC, HNSC, and LIHC are the cancer types where LINC00869 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00869 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.497	<.001	8	view →
HNSC	All	All	+0.203	.001	7	view →
LIHC	Male	All	+0.899	<.001	6	view →
THCA	All	All	+0.277	.002	4	view →
CHOL	All	All	+0.870	.001	3	view →
KICH	All	All	−0.295	.007	3	view →
LUSC	Male	III,IV	−0.602	.008	2	view →
PRAD	All	All	+0.388	<.001	2	view →
LUAD	All	All	+0.252	.004	2	view →
ESCA	Male	All	+0.419	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC00869–KIRC

Open the KIRC breakdown →