LINC00869

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00869 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00869-associated genes across cancer lineages are ASNS, Cyclin-B1, and GAPDH. Each is linked with LINC00869 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00869-to-partner and partner-to-LINC00869 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by LINC00869-low versus LINC00869-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00869→partner) and Y-score (partner→LINC00869) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADASNS →+0.848+2.815<.001.03632
UCECCyclin-B1 →+0.775+3.906<.001<.00132
COADGAPDH →+0.902+2.820.001.03531
COADp70-S6K →+0.353+2.832.012.03531
COADPTEN →+0.217+2.815.004.03631
UCECEGFR →-0.144-2.321.016.03431
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ASNS by LINC00869 expression — COAD

Box plot of ASNS in LINC00869-low vs LINC00869-high samples in COAD.

Explore this box plot interactively →

Exploration