LINC00868

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00868 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00868-associated genes across cancer lineages are RNA5SP124, RNU6-508P, and RNU6-1138P. Each is linked with LINC00868 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00868-to-partner and partner-to-LINC00868 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP124 grouped by LINC00868-low versus LINC00868-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00868→partner) and Y-score (partner→LINC00868) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP124 →+0.562+3.581.001.00431
UCECRNU6-508P →+0.479+4.453<.001.00631
UCECRNU6-1138P →+0.367+4.081.002.00231
UCECC7orf66 →+0.468+3.671<.001.00331
UCECRNU6-1292P →+0.545+4.453<.001.00631
UCECRNU6-32P →+0.682+4.233.003.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

RNA5SP124 by LINC00868 expression — UCEC

Box plot of RNA5SP124 in LINC00868-low vs LINC00868-high samples in UCEC.

Explore this box plot interactively →

Exploration