LINC00868

Across TCGA pan-cancer cohorts, LINC00868 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC00868 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00868 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00868 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

KIRC, KICH, and KIRP are the cancer types where LINC00868 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.493	0.702	<.001	164	view →
KICH	OS	Tertile	All	0.806	0.992	.003	63	view →
KIRP	OS	Tertile	All	0.848	0.952	.002	60	view →
COAD	OS	Tertile	All	0.369	0.648	.002	45	view →
HNSC	DFS	Quartile	IV	0.773	0.597	.003	35	view →
LUAD	OS	Tertile	II,III,IV	0.107	0.314	.021	31	view →
THCA	DFS	Quartile	II,III,IV	0.721	0.878	.001	31	view →
LUSC	DFS	Tertile	II,III,IV	0.572	0.814	.006	25	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	24	view →
LGG	DFS	Median	All	0.763	0.871	.002	15	view →
BRCA	OS	Quartile	All	0.985	0.945	.002	13	view →
DLBC	OS	Tertile	All	0.586	0.824	.033	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LINC00868–KIRC (DFS)

Open the KIRC breakdown →