LINC00686

Across TCGA pan-cancer cohorts, LINC00686 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated LINC00686 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher LINC00686 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00686 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

KIRP, UCEC, and KICH are the cancer types where LINC00686 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.255	0.778	<.001	105	view →
UCEC	OS	Quartile	II,III,IV	0.733	0.887	.002	86	view →
KICH	OS	Tertile	All	0.793	0.949	.003	81	view →
LUAD	DFS	Tertile	All	0.631	0.800	.004	72	view →
PCPG	DFS	Tertile	All	0.458	0.909	<.001	45	view →
KIRC	DFS	Tertile	II,III,IV	0.172	0.663	.006	36	view →
BLCA	DFS	Tertile	IV	0.145	0.479	.020	27	view →
LUSC	OS	Tertile	All	0.472	0.769	.006	24	view →
ACC	OS	Tertile	All	0.118	0.624	.038	18	view →
SKCM	DFS	Tertile	All	0.267	0.184	.037	7	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

LINC00686–KIRP (OS)

Open the KIRP breakdown →