LINC00648

Across TCGA pan-cancer cohorts, LINC00648 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated LINC00648 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher LINC00648 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00648 expression acts as an unfavorable survival marker, although some lineages such as UVM and BRCA show a favorable association.

KICH, KIRC, and LUSC are the cancer types where LINC00648 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	II,III,IV	0.492	0.934	<.001	104	view →
KIRC	OS	Median	All	0.754	0.850	<.001	94	view →
LUSC	DFS	Tertile	II,III,IV	0.651	0.829	<.001	83	view →
ACC	OS	Quartile	All	0.319	0.765	<.001	59	view →
KIRP	DFS	Quartile	All	0.339	0.695	<.001	51	view →
LIHC	OS	Quartile	All	0.675	0.824	.001	42	view →
UVM	DFS	Median	All	0.698	0.471	.003	38	view →
BRCA	OS	Quartile	III,IV	0.943	0.765	<.001	37	view →
UCEC	OS	Tertile	All	0.895	0.945	.005	24	view →
UCS	DFS	Tertile	III,IV	0.438	0.111	.032	18	view →
BLCA	DFS	Median	All	0.560	0.665	.007	17	view →
LGG	OS	Quartile	All	0.855	0.977	.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

LINC00648–KICH (DFS)

Open the KICH breakdown →