LINC00648

Across TCGA pan-cancer cohorts, LINC00648 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC00648’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC00648 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00648 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

LIHC, KICH, and BRCA are the cancer types where LINC00648 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00648 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.358	<.001	5	view →
KICH	All	All	−0.154	<.001	5	view →
BRCA	All	All	−0.311	<.001	4	view →
HNSC	All	All	+0.209	.014	4	view →
LUSC	All	All	+0.508	.002	3	view →
LUAD	All	All	+0.420	.003	3	view →
COAD	Female	All	−0.107	.001	2	view →
READ	All	All	−0.112	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC00648–LIHC

Open the LIHC breakdown →