LINC00645

Across TCGA pan-cancer cohorts, LINC00645 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC00645 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LINC00645 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00645 expression acts as an unfavorable survival marker, although some lineages such as UVM and MESO show a favorable association.

COAD, UVM, and MESO are the cancer types where LINC00645 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.432	0.722	<.001	126	view →
UVM	OS	Median	All	0.806	0.434	<.001	81	view →
MESO	OS	Median	IV	0.895	0.352	<.001	48	view →
STAD	OS	Quartile	II,III,IV	0.532	0.699	.010	36	view →
READ	DFS	Tertile	IV	0.209	0.691	<.001	36	view →
LGG	OS	Median	All	0.931	0.856	<.001	35	view →
KICH	DFS	Tertile	III,IV	1.000	0.274	.003	26	view →
LUSC	OS	Median	II,III,IV	0.483	0.322	.006	25	view →
BRCA	OS	Tertile	II,III,IV	0.340	0.622	.002	18	view →
ESCA	OS	Median	All	1.000	0.659	.020	18	view →
DLBC	OS	Tertile	IV	0.147	0.850	.002	18	view →
GBM	DFS	Median	All	0.250	0.158	.010	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC00645–COAD (DFS)

Open the COAD breakdown →