LINC00635

Across TCGA pan-cancer cohorts, LINC00635 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00635’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC00635 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00635 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA, LUSC, and KIRP are the cancer types where LINC00635 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00635 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.013	.002	6	view →
LUSC	All	All	+0.008	.036	2	view →
KIRP	All	All	+0.158	.010	1	view →
THCA	All	All	+0.019	.015	1	view →
HNSC	Female	IV	+0.011	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC00635–BRCA

Open the BRCA breakdown →