LINC00628

Across TCGA patient cohorts, LINC00628 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,313 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00628-associated proteins across cancer lineages are PLEKHA6_S777, PLEKHA6, and PLEKHA6_S459. Each is linked with LINC00628 in more than 4 cancer types. Because this analysis shows association rather than direction, both LINC00628-to-partner and partner-to-LINC00628 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC00628 versus PLEKHA6_S777 in PDAC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00628→partner) and Y-score (partner→LINC00628) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLEKHA6_S777 →	+0.839	+0.312	<.001	<.001	3	5
UCEC	PLEKHA6 →	+0.584	+0.651	<.001	<.001	3	4
LSCC	PLEKHA6_S459 →	+0.812	+0.200	<.001	<.001	3	4
CCRCC	LACTB2 →	+0.408	+0.438	<.001	<.001	3	4
UCEC	PLEKHA6_S808 →	+0.578	+0.386	.005	.002	3	3
PDAC	PLS1 →	+0.596	+0.475	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,313 associations by consensus.

LINC00628 vs PLEKHA6_S777 — PDAC

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