LINC00628

Across TCGA pan-cancer cohorts, LINC00628 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of LINC00628’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC00628 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00628 is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

LUAD, KIRC, and STAD are the cancer types where LINC00628 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00628 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.298	<.001	11	view →
KIRC	Male	IV	+0.274	<.001	11	view →
STAD	All	All	+0.402	<.001	9	view →
BLCA	Male	All	+0.549	<.001	8	view →
LIHC	Male	All	+0.289	<.001	8	view →
COAD	Female	II,III,IV	+0.451	<.001	7	view →
KIRP	Male	II,III,IV	+0.429	<.001	7	view →
BRCA	All	II,III,IV	+0.212	<.001	6	view →
HNSC	All	III,IV	−0.110	.008	6	view →
KICH	Female	All	−0.155	<.001	5	view →
LUSC	All	All	+0.138	.001	4	view →
THCA	All	All	+0.025	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

LINC00628–LUAD

Open the LUAD breakdown →