LINC00589

Across TCGA pan-cancer cohorts, LINC00589 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC00589 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher LINC00589 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00589 expression acts as an unfavorable survival marker, although some lineages such as ACC and BRCA show a favorable association.

ACC, LUAD, and TGCT are the cancer types where LINC00589 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	II,III,IV	0.651	0.226	<.001	77	view →
LUAD	OS	Median	III,IV	0.365	0.640	<.001	65	view →
TGCT	DFS	Quartile	II,III,IV	0.364	1.000	<.001	50	view →
GBM	OS	Tertile	All	0.314	0.489	<.001	39	view →
KIRP	DFS	Tertile	III,IV	0.473	0.804	.004	36	view →
MESO	DFS	Quartile	All	0.223	0.403	<.001	35	view →
ESCA	OS	Median	IV	0.222	0.698	.006	21	view →
LGG	OS	Quartile	All	0.727	0.839	.003	20	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	10	view →
STAD	DFS	Tertile	IV	0.126	0.575	.020	9	view →
SKCM	DFS	Quartile	IV	0.048	0.456	.010	6	view →
BRCA	DFS	Median	IV	0.675	0.354	.017	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC00589–ACC (DFS)

Open the ACC breakdown →