LINC00581

Across TCGA patient cohorts, LINC00581 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,781 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00581-associated GO terms across cancer lineages are Positive regulation of DNA repair, Mitochondrial gene expression, and Establishment of protein localization to mitochondrial membrane. Each is linked with LINC00581 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC00581-to-partner and partner-to-LINC00581 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by LINC00581-low versus LINC00581-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00581→partner) and Y-score (partner→LINC00581) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.067	+0.172	<.001	<.001	3	14
STAD	Mitochondrial gene expression →	+0.077	+0.163	<.001	<.001	3	14
STAD	Establishment of protein localization to mitochondrial membrane →	+0.072	+0.161	<.001	<.001	3	14
STAD	Methylation →	+0.062	+0.173	<.001	<.001	3	13
STAD	Mitochondrial translation →	+0.080	+0.145	<.001	<.001	3	13
STAD	Mitochondrial respiratory chain complex assembly →	+0.079	+0.168	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,781 associations by consensus.

Positive regulation of DNA repair by LINC00581 expression — STAD

Explore this box plot interactively →