LINC00581

Across TCGA pan-cancer cohorts, LINC00581 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LINC00581 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher LINC00581 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00581 expression acts as an unfavorable survival marker, although some lineages such as LUAD and THCA show a favorable association.

STAD, UCEC, and LUSC are the cancer types where LINC00581 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Quartile	III,IV	0.163	0.509	.001	50	view →
UCEC	DFS	Tertile	All	0.547	0.676	<.001	50	view →
LUSC	OS	Tertile	III,IV	0.142	0.437	<.001	50	view →
LUAD	OS	Median	All	0.530	0.287	<.001	33	view →
THCA	DFS	Tertile	All	0.935	0.715	.005	31	view →
UCS	OS	Tertile	II,III,IV	0.754	0.362	.014	30	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	30	view →
CESC	DFS	Tertile	II,III,IV	0.857	0.644	.018	30	view →
KIRP	DFS	Tertile	All	0.840	0.951	.002	29	view →
BLCA	OS	Tertile	III,IV	0.617	0.350	.008	18	view →
UVM	DFS	Tertile	III,IV	0.232	0.675	.009	14	view →
OV	OS	Quartile	II,III,IV	0.857	0.783	.022	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LINC00581–STAD (DFS)

Open the STAD breakdown →