LINC00561

Across TCGA patient cohorts, LINC00561 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,718 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00561-associated GO terms across cancer lineages are Negative regulation of cell cycle G1/S phase transition, Regulation of epithelial to mesenchymal transition, and Striated muscle cell proliferation. Each is linked with LINC00561 in more than 11 cancer types. Because this analysis shows association rather than direction, both LINC00561-to-partner and partner-to-LINC00561 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle G1/S phase transition grouped by LINC00561-low versus LINC00561-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00561→partner) and Y-score (partner→LINC00561) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of cell cycle G1/S phase transition →	+0.067	+0.102	<.001	.002	3	12
TGCT	Regulation of epithelial to mesenchymal transition →	+0.076	+0.090	<.001	<.001	3	12
TGCT	Striated muscle cell proliferation →	+0.057	+0.047	<.001	<.001	3	12
TGCT	Negative regulation of canonical Wnt signaling pathway →	+0.076	+0.052	<.001	<.001	3	12
TGCT	Osteoblast differentiation →	+0.061	+0.087	<.001	<.001	3	12
ESCA	Cellular oxidant detoxification →	+0.066	+0.103	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,718 associations by consensus.

Negative regulation of cell cycle G1/S phase transition by LINC00561 expression — ESCA

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