LINC00561

Across TCGA pan-cancer cohorts, LINC00561 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00561’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LINC00561 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00561 is over-expressed in tumor, although a few such as BLCA and HNSC show the opposite, repressed pattern.

BLCA, HNSC, and BRCA are the cancer types where LINC00561 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00561 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−0.058	<.001	11	view →
HNSC	All	All	−0.017	.001	8	view →
BRCA	All	All	−0.019	<.001	6	view →
STAD	All	All	−0.076	.033	2	view →
READ	Female	All	−0.032	.005	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC00561–BLCA

Open the BLCA breakdown →