LINC00558

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00558 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,106 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00558-associated GO terms across cancer lineages are tRNA metabolic process, DNA-templated transcription elongation, and Positive regulation of peptidase activity. Each is linked with LINC00558 in more than 10 cancer types. Because this analysis shows association rather than direction, both LINC00558-to-partner and partner-to-LINC00558 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by LINC00558-low versus LINC00558-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00558→partner) and Y-score (partner→LINC00558) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADtRNA metabolic process →+0.088+0.055<.001<.001311
STADDNA-templated transcription elongation →+0.096+0.059<.001<.001310
STADPositive regulation of peptidase activity →+0.076+0.056<.001<.00139
STADMethylation →+0.080+0.066<.001<.00139
STADRegulation of transcription elongation by RNA polymerase II →+0.094+0.054<.001<.00139
STADDendritic spine development →+0.056+0.052<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,106 associations by consensus.

tRNA metabolic process by LINC00558 expression — STAD

Box plot of tRNA metabolic process in LINC00558-low vs LINC00558-high samples in STAD.

Explore this box plot interactively →

Exploration