LINC00557

Across TCGA patient cohorts, LINC00557 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,636 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00557-associated GO terms across cancer lineages are Microtubule polymerization, Negative regulation of DNA metabolic process, and snRNA metabolic process. Each is linked with LINC00557 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC00557-to-partner and partner-to-LINC00557 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by LINC00557-low versus LINC00557-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00557→partner) and Y-score (partner→LINC00557) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule polymerization →	+0.056	+0.033	<.001	<.001	3	14
STAD	Negative regulation of DNA metabolic process →	+0.055	+0.032	<.001	<.001	3	14
STAD	snRNA metabolic process →	+0.065	+0.032	<.001	<.001	3	14
ESCA	Microtubule organizing center organization →	+0.065	+0.092	<.001	<.001	3	14
STAD	Regulation of organelle assembly →	+0.063	+0.034	<.001	<.001	3	13
STAD	Positive regulation of DNA-templated transcription initiation →	+0.067	+0.037	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,636 associations by consensus.

Microtubule polymerization by LINC00557 expression — STAD

Explore this box plot interactively →