LINC00544

Across TCGA pan-cancer cohorts, LINC00544 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC00544 data layer compared with 1 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher LINC00544 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC00544 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

SKCM, CESC, and BLCA are the cancer types where LINC00544 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.426	0.283	<.001	105	view →
CESC	DFS	Quartile	All	0.942	0.747	<.001	56	view →
BLCA	OS	Median	III,IV	0.632	0.346	.008	53	view →
PAAD	OS	Median	II,III,IV	0.698	0.476	<.001	50	view →
LGG	DFS	Median	All	0.308	0.493	<.001	43	view →
UVM	OS	Tertile	II,III,IV	0.343	0.680	.008	42	view →
GBM	DFS	Median	All	0.187	0.372	.004	30	view →
READ	OS	Tertile	II,III,IV	0.731	0.959	.002	29	view →
LUAD	OS	Quartile	II,III,IV	0.766	0.489	.007	29	view →
HNSC	DFS	Median	II,III,IV	0.672	0.467	.010	27	view →
KICH	OS	Median	All	1.000	0.692	.004	27	view →
ESCA	OS	Quartile	III,IV	0.723	0.336	.012	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC00544–SKCM (OS)

Open the SKCM breakdown →