LINC00544

Across TCGA pan-cancer cohorts, LINC00544 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC00544’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00544 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00544 is over-expressed in tumor, although a few such as PAAD and LUAD show the opposite, repressed pattern.

KIRC, PAAD, and BRCA are the cancer types where LINC00544 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00544 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.155	<.001	11	view →
PAAD	All	All	−0.270	.027	4	view →
BRCA	All	All	+0.036	.016	3	view →
LUAD	All	All	+0.074	.025	2	view →
LUAD	Female	III,IV	−0.099	.029	1	view →
THCA	Male	All	+0.066	.026	1	view →
STAD	All	All	+0.049	.049	1	view →
COAD	Female	III,IV	−0.030	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 7 lineages.

LINC00544–KIRC

Open the KIRC breakdown →