LINC00525

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00525 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00525-associated genes across cancer lineages are EIF1AY, RPS29P6, and MTCO3P41. Each is linked with LINC00525 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00525-to-partner and partner-to-LINC00525 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF1AY grouped by LINC00525-low versus LINC00525-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00525→partner) and Y-score (partner→LINC00525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEIF1AY →+0.058+4.374<.001.00731
UCECRPS29P6 →+1.009+4.771<.001.00631
UCECMTCO3P41 →+0.313+5.073.001.00131
UCECSAP18P1 →+0.170+4.551<.001.00931
UCECLYPLA1P2 →+0.142+4.423.007.00631
UCECOR5M1 →+0.092+7.167<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

EIF1AY by LINC00525 expression — UCEC

Box plot of EIF1AY in LINC00525-low vs LINC00525-high samples in UCEC.

Explore this box plot interactively →

Exploration