LINC00500

Across TCGA pan-cancer cohorts, LINC00500 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated LINC00500 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher LINC00500 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00500 expression acts as an unfavorable survival marker, although some lineages such as TGCT and ESCA show a favorable association.

KIRP, HNSC, and KIRC are the cancer types where LINC00500 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.488	0.854	<.001	69	view →
HNSC	DFS	Tertile	All	0.297	0.572	.002	36	view →
KIRC	DFS	Tertile	All	0.350	0.650	.006	12	view →
BRCA	OS	Tertile	III,IV	0.397	0.574	.031	6	view →
TGCT	DFS	Tertile	All	0.777	0.621	.042	6	view →
THCA	OS	Tertile	All	0.375	0.948	.030	6	view →
ESCA	OS	Quartile	III,IV	0.773	0.365	.044	2	view →
DLBC	DFS	Median	III,IV	1.000	0.440	.022	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

LINC00500–KIRP (OS)

Open the KIRP breakdown →