LINC00494

Across TCGA pan-cancer cohorts, LINC00494 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC00494 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00494 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00494 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

UVM, LUAD, and HNSC are the cancer types where LINC00494 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.422	0.843	<.001	91	view →
LUAD	DFS	Median	All	0.729	0.601	<.001	90	view →
HNSC	DFS	Tertile	IV	0.746	0.549	<.001	81	view →
LGG	OS	Median	All	0.868	0.746	<.001	45	view →
READ	OS	Median	All	1.000	0.838	<.001	38	view →
CESC	OS	Tertile	All	0.927	0.827	.015	32	view →
UCEC	OS	Tertile	All	0.585	0.808	.007	24	view →
SARC	DFS	Tertile	All	0.703	0.523	.003	23	view →
DLBC	DFS	Tertile	All	0.509	1.000	.004	20	view →
CHOL	OS	Tertile	All	0.892	0.220	.005	19	view →
KIRP	DFS	Tertile	IV	0.035	0.686	.013	18	view →
BRCA	OS	Quartile	IV	0.986	0.425	.007	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LINC00494–UVM (DFS)

Open the UVM breakdown →