LINC00488

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00488 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC00488 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00488 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00488 expression acts as an unfavorable survival marker, although some lineages such as OV and CESC show a favorable association.

KIRC, ACC, and KICH are the cancer types where LINC00488 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.5280.727<.00164view →
ACCDFSTertileAll0.0830.647<.00160view →
KICHDFSTertileII,III,IV0.3480.843<.00154view →
OVOSMedianIV0.9020.612.00450view →
KIRPDFSMedianAll0.8680.963.00242view →
CESCOSQuartileIV0.8010.199.01924view →
LUSCDFSTertileIII,IV0.1680.777.01418view →
ESCAOSMedianIII,IV0.5520.335.02818view →
DLBCOSTertileIII,IV0.2721.000.03815view →
LGGOSTertileAll0.7120.849<.00114view →
LIHCDFSMedianAll0.2100.412.00513view →
UCSOSTertileIV0.9920.590.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration