LINC00461

Across TCGA patient cohorts, LINC00461 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00461-associated genes across cancer lineages are MIR3193, CCDC58P3, and EML2-AS1. Each is linked with LINC00461 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00461-to-partner and partner-to-LINC00461 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3193 grouped by LINC00461-low versus LINC00461-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00461→partner) and Y-score (partner→LINC00461) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3193 →	+1.294	+3.838	<.001	<.001	3	1
UCEC	CCDC58P3 →	+0.412	+3.372	<.001	.008	3	1
UCEC	EML2-AS1 →	+0.138	+2.592	<.001	.009	3	1
UCEC	H3Y2 →	+0.683	+2.563	<.001	.009	3	1
UCEC	MIA-RAB4B →	+0.127	+2.863	<.001	.004	3	1
UCEC	RPS29P32 →	+0.605	+3.277	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MIR3193 by LINC00461 expression — UCEC

Explore this box plot interactively →