Across TCGA patient cohorts, LINC00459 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,349 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00459-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Ribose phosphate biosynthetic process, and Telomere maintenance in response to DNA damage. Each is linked with LINC00459 in more than 7 cancer types. Because this analysis shows association rather than direction, both LINC00459-to-partner and partner-to-LINC00459 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00459→partner) and Y-score (partner→LINC00459) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of mRNA processing →	+0.100	+0.215	<.001	<.001	3	8
STAD	Ribose phosphate biosynthetic process →	+0.095	+0.189	<.001	<.001	3	8
ESCA	Telomere maintenance in response to DNA damage →	+0.089	+0.206	<.001	<.001	3	8
ESCA	Regulation of telomere maintenance in response to DNA damage →	+0.089	+0.120	<.001	<.001	3	8
ESCA	Proton-transporting two-sector ATPase complex assembly →	+0.073	+0.202	<.001	<.001	3	7
STAD	Protein localization to mitochondrion →	+0.095	+0.207	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,349 associations by consensus.

Exploration

LINC00459 survival (RNA) · tumor vs normal (RNA) · all LINC00459 data types